However, MV can contribute to a worsening of the primary lung injury, known as ventilation-induced lung injury (VILI), which could have an important impact on outcome. Mechanical ventilation (MV) is a lifesaving supportive intervention in the management of acute respiratory distress syndrome (ARDS), buying time while the primary precipitating cause is being corrected. 8Department of Anesthesiology, Hospital Privado de Comunidad, Mar del Plata, Argentina.7Hospital Clinic, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.6Department of Anesthesiology and Critical Care, Hospital Clinic, Barcelona, Spain.5Keenan Research Center at the Li Ka Shing Knowledge Institute, St.Negrín, Las Palmas de Gran Canaria, Spain 4Multidisciplinary Organ Dysfunction Evaluation Research Network (MODERN), Research Unit, Hospital Universitario Dr.3Department of Surgical Sciences, Anesthesiology & Critical Care, Hedenstierna Laboratory, Uppsala University Hospital, Uppsala, Sweden. 2Intensive Care Unit, Hospital Universitario La Princesa, Madrid, Spain.1CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.Fernando Suárez-Sipmann 1,2,3*† Jesús Villar 1,4,5† Carlos Ferrando 1,6,7† Juan A.
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